COMPUTATIONAL LIFE EXPERIENCE

WHAT WE DO?

Computational Life’s technology enables to simulate the interactions of medical devices on a Digital Avatar of the human body, providing safety and efficacy results to MedTech before creating a single prototype.

Our technology accelerates the entire development of medical devices leveraging a parametric, statistical, and patient-specific analysis.

We are developing patient populations to run full in-silico clinical trials to de-risk medical innovations and improve efficacy by better defining exclusion and inclusion criteria.

MATHEMATICS AND MEDICINE COME TOGETHER

DIGITAL REVOLUTION

Towards In-Silico Clinical Trials

Quantify the effect of medical devices in a cohort of a virtual population has always been challenging in the modeling community for the lack of coupled interactive dynamics. 

A whole-body physiological model, coupled with a multiscale model of the whole body (3D-0D-1D) will enable the company to quantify the human response in a virtual population of human bodies

MATHEMATICS AND MEDICINE COME TOGETHER

SOFTWARE VALIDATION

Computational Life’s software replicates all body fluid mechanisms into a single, integrated platform based on the state-of-the-art of mathematical modeling. Our software is currently able to simultaneously simulate the dynamics of the:

• Arterial and venous system;
• Heart;
• Microcirculation;
• Pulmonary circulation;
• Cerebrospinal fluid;

The mathematical modeling relies on basic validated physical laws of fluid dynamics. The hemodynamics of the Digital Avatar have been validated using peer-reviewed articles in the healthy human body, and the computational waveforms closely resemble in-vivo measurements in healthy subjects.